Predicting RTS,S Vaccine-Mediated Protection from Transcriptomes in a Malaria-Challenge Clinical Trial

Predicting RTS,S Vaccine-Mediated Protection from Transcriptomes in a Malaria-Challenge Clinical Trial

The RTS,S candidate malaria vaccine can protect against controlled human malaria infection (CHMI), but how protection is achieved remains unclear. Here, we have analyzed longitudinal peripheral blood transcriptome and immunogenicity data from a clinical efficacy trial in which healthy adults receive...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Robert A. van den Berg, Margherita Coccia, W. Ripley Ballou, Kent E. Kester, Christian F. Ockenhouse, Johan Vekemans, Erik Jongert, Arnaud M. Didierlaurent, Robbert G. van der Most
বিন্যাস: প্রবন্ধ
ভাষা:English
প্রকাশিত: Frontiers Media S.A. 2017-05-01
মালা:Frontiers in Immunology
বিষয়গুলি:
malaria
systems biology
transcriptome
vaccine
clinical trial
interferon gamma
অনলাইন ব্যবহার করুন:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00557/full

আন্তর্জাল

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00557/full

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