FGF23 regulates renal sodium handling and blood pressure

FGF23 regulates renal sodium handling and blood pressure

Abstract Fibroblast growth factor‐23 (FGF23) is a bone‐derived hormone regulating renal phosphate reabsorption and vitamin D synthesis in renal proximal tubules. Here, we show that FGF23 directly regulates the membrane abundance of the Na+:Cl− co‐transporter NCC in distal renal tubules by a signalin...

Full description

Bibliographic Details
Main Authors: Olena Andrukhova, Svetlana Slavic, Alina Smorodchenko, Ute Zeitz, Victoria Shalhoub, Beate Lanske, Elena E Pohl, Reinhold G Erben
Format: Article
Language:English
Published: Springer Nature 2014-06-01
Series:EMBO Molecular Medicine
Subjects:
aldosterone
blood pressure
fibroblast growth factor‐23
heart hypertrophy
sodium homeostasis
Online Access:https://doi.org/10.1002/emmm.201303716

Internet

https://doi.org/10.1002/emmm.201303716

Similar Items