Development of the CRISPR-Cas9 System for the Marine-Derived Fungi <i>Spiromastix</i> sp. SCSIO F190 and <i>Aspergillus</i> sp. SCSIO SX7S7

Development of the CRISPR-Cas9 System for the Marine-Derived Fungi <i>Spiromastix</i> sp. SCSIO F190 and <i>Aspergillus</i> sp. SCSIO SX7S7

Marine-derived fungi are emerging as attractive producers of structurally novel secondary metabolites with diverse bioactivities. However, the lack of efficient genetic tools limits the discovery of novel compounds and the elucidation of biosynthesis mechanisms. Here, we firstly established an effec...

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Bibliographic Details
Main Authors: Yingying Chen, Cunlei Cai, Jiafan Yang, Junjie Shi, Yongxiang Song, Dan Hu, Junying Ma, Jianhua Ju
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Journal of Fungi
Subjects:
marine-derived fungi
CRISPR-Cas9
<i>Spiromastix</i> sp. SCSIO F190
<i>Aspergillus</i> sp. SCSIO SX7S7
secondary metabolites
histone deacetylase
Online Access:https://www.mdpi.com/2309-608X/8/7/715

Internet

https://www.mdpi.com/2309-608X/8/7/715

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