Leptin enhances cytokine/chemokine production by normal lung fibroblasts by binding to leptin receptor

Background: Obesity is a known risk and exacerbation factor for bronchial asthma. Leptin is an adipokine secreted by adipocytes and enhances energy consumption. Earlier studies have shown that leptin also activates inflammatory cells and structural cells, including airway epithelial cells, thereby e...

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Bibliographic Details
Main Authors: Kaoru Watanabe, Maho Suzukawa, Sayaka Arakawa, Koichi Kobayashi, Sayaka Igarashi, Hiroyuki Tashimo, Hideaki Nagai, Shigeto Tohma, Takahide Nagase, Ken Ohta
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Allergology International
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893019300486