Phosphorylation of transglutaminase 2 (TG2) at serine-216 has a role in TG2 mediated activation of nuclear factor-kappa B and in the downregulation of PTEN

<p>Abstract</p> <p>Background</p> <p>Transglutaminase 2 (TG2) and its phosphorylation have been consistently found to be upregulated in a number of cancer cell types. At the molecular level, TG2 has been associated with the activation of nuclear factor-kappa B (NF-κB),...

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Bibliographic Details
Main Authors: Wang Yi, Ande Sudharsana R, Mishra Suresh
Format: Article
Language:English
Published: BMC 2012-07-01
Series:BMC Cancer
Subjects:
Online Access:http://www.biomedcentral.com/1471-2407/12/277