Viral delivery of a peptide-based immunomodulator enhances T cell priming during vaccination
Modern, subunit-based vaccines have so far failed to induce significant T cell responses, contributing to ineffective vaccination against many pathogens. Importantly, while today’s adjuvants are designed to trigger innate and non-specific immune responses, they fail to directly stimulate the adaptiv...
Main Authors: | Timothy W. Phares, Jing Huang, Vinayaka Kotraiah, Mary J. Hauser, Arban Domi, Sreenivasa Oruganti, Cecille D. Browne, Peter Buontempo, Marc Mansour, James Pannucci, Moriya Tsuji, Gabriel M. Gutierrez |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-12-01
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Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2022.1029636/full |
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