HSP47 Increases the Expression of Type I Collagen in Fibroblasts through IRE1α Activation, XBP1 Splicing, and Nuclear Translocation of β-Catenin

Heat shock protein 47 (HSP47), also known as <i>SERPINH1</i>, functions as a collagen-specific molecular chaperone protein essential for the formation and stabilization of the collagen triple helix. Here, we delved into the regulatory pathways governed by HSP47, shedding light on collage...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: So Young Ham, Min Ju Pyo, Moonkyung Kang, Yeon-Soo Kim, Dong Hun Lee, Jin Ho Chung, Seung-Taek Lee
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: MDPI AG 2024-03-01
Cyfres:Cells
Pynciau:
Mynediad Ar-lein:https://www.mdpi.com/2073-4409/13/6/527