HSP47 Increases the Expression of Type I Collagen in Fibroblasts through IRE1α Activation, XBP1 Splicing, and Nuclear Translocation of β-Catenin
Heat shock protein 47 (HSP47), also known as <i>SERPINH1</i>, functions as a collagen-specific molecular chaperone protein essential for the formation and stabilization of the collagen triple helix. Here, we delved into the regulatory pathways governed by HSP47, shedding light on collage...
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Fformat: | Erthygl |
Iaith: | English |
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MDPI AG
2024-03-01
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Cyfres: | Cells |
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Mynediad Ar-lein: | https://www.mdpi.com/2073-4409/13/6/527 |