Fibrosis-associated hepatocarcinogenesis revisited: Establishing standard medium-term chemically-induced male and female models.

Fibrosis-associated hepatocarcinogenesis revisited: Establishing standard medium-term chemically-induced male and female models.

Hepatocellular carcinoma causes ~10% of all cancer-related deaths worldwide, usually emerging in a background of liver fibrosis/cirrhosis (70%-90% of cases). Chemically-induced mouse models for fibrosis-associated hepatocarcinogenesis are widely-applied, resembling the corresponding human disease. N...

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Bibliographic Details
Main Authors: Guilherme Ribeiro Romualdo, Gabriel Bacil Prata, Tereza Cristina da Silva, Ana Angélica Henrique Fernandes, Fernando Salvador Moreno, Bruno Cogliati, Luís Fernando Barbisan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6136798?pdf=render

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http://europepmc.org/articles/PMC6136798?pdf=render

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