A surprisingly poor correlation between in vitro and in vivo testing of biomaterials for bone regeneration: results of a multicentre analysis

A surprisingly poor correlation between in vitro and in vivo testing of biomaterials for bone regeneration: results of a multicentre analysis

New regenerative materials and approaches need to be assessed through reliable and comparable methods for rapid translation to the clinic. There is a considerable need for proven in vitro assays that are able to reduce the burden on animal testing, by allowing assessment of biomaterial utility predi...

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Bibliographic Details
Main Authors: G Hulsart-Billström, JI Dawson, S Hofmann, R Müller, MJ Stoddart, M Alini, H Redl, A El Haj, R Brown, V Salih, J Hilborn, S Larsson, ROC Oreffo
Format: Article
Language:English
Published: Forum Multimedia Publishing LLC 2016-05-01
Series:European Cells & Materials
Subjects:
in vivo
in vitro
correlation
biomaterials
multicentre study
Online Access:http://www.ecmjournal.org/papers/vol031/pdf/v031a20.pdf

Internet

http://www.ecmjournal.org/papers/vol031/pdf/v031a20.pdf

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