Programmed spatial organization of biomacromolecules into discrete, coacervate-based protocells

Mimicking the crowded cytosol of cells in synthetic cells has been a major limitation to the functionality. Here, the authors used the interaction between nickel, nitrilotriacetic acid and histidine tagged proteins to control loading of macromolecules into spatially programmed coacervate-based proto...

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Bibliographic Details
Main Authors: Wiggert J. Altenburg, N. Amy Yewdall, Daan F. M. Vervoort, Marleen H. M. E. van Stevendaal, Alexander F. Mason, Jan C. M. van Hest
Format: Article
Language:English
Published: Nature Portfolio 2020-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20124-0