GC content around splice sites affects splicing through pre-mRNA secondary structures

<p>Abstract</p> <p>Background</p> <p>Alternative splicing increases protein diversity by generating multiple transcript isoforms from a single gene through different combinations of exons or through different selections of splice sites. It has been reported that RNA sec...

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Bibliographic Details
Main Authors: Chen Liang, Kuo CC Jay, Zhang Jing
Format: Article
Language:English
Published: BMC 2011-01-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/12/90