Diffusible Tumor Necrosis Factor-Alpha (TNF-α) Promotes Noise-Induced Parvalbumin-Positive (PV+) Neuron Loss and Auditory Processing Impairments

Diffusible Tumor Necrosis Factor-Alpha (TNF-α) Promotes Noise-Induced Parvalbumin-Positive (PV+) Neuron Loss and Auditory Processing Impairments

Neuroinflammation has been implicated in noise-induced auditory processing disorder and tinnitus. Certain non-auditory neurological disorders can also increase the levels of proinflammatory cytokines in the brain. To investigate the impact of increased brain proinflammatory cytokine levels on the ce...

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Bibliographic Details
Main Authors: Di Deng, Weihua Wang, Shaowen Bao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Neuroscience
Subjects:
hearing loss
TNF-α
parvalbumin-positive neuron
microglia
auditory processing
tinnitus
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.573047/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2020.573047/full

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