Comparison of Detailed and Simplified Models of Human Atrial Myocytes to Recapitulate Patient Specific Properties.

Computer studies are often used to study mechanisms of cardiac arrhythmias, including atrial fibrillation (AF). A crucial component in these studies is the electrophysiological model that describes the membrane potential of myocytes. The models vary from detailed, describing numerous ion channels, t...

Full description

Bibliographic Details
Main Authors: Daniel M Lombardo, Flavio H Fenton, Sanjiv M Narayan, Wouter-Jan Rappel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-08-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4975409?pdf=render