Antibody fragments functionalized with non-canonical amino acids preserving structure and functionality - A door opener for new biological and therapeutic applications

Antibody fragments functionalized with non-canonical amino acids preserving structure and functionality - A door opener for new biological and therapeutic applications

Functionalization of proteins by incorporating reactive non-canonical amino acids (ncAAs) has been widely applied for numerous biological and therapeutic applications. The requirement not to lose the intrinsic properties of these proteins is often underestimated and not considered. Main purpose of t...

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Bibliographic Details
Main Authors: Hana Hanaee-Ahvaz, Monika Cserjan-Puschmann, Florian Mayer, Christopher Tauer, Bernd Albrecht, Paul G. Furtmüller, Birgit Wiltschi, Rainer Hahn, Gerald Striedner
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Heliyon
Subjects:
E. coli
Non-canonical amino acids
Antigen binding fragment
Micro-bioreactor cultivations
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023096718

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http://www.sciencedirect.com/science/article/pii/S2405844023096718

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