Case report: Two PD-L1 positive unresectable advanced pancreatic carcinoma patients with microsatellite stability achieved R0 resection after PD-1 antibody plus chemotherapy as a successful downstaging therapy: A report of two cases

Case report: Two PD-L1 positive unresectable advanced pancreatic carcinoma patients with microsatellite stability achieved R0 resection after PD-1 antibody plus chemotherapy as a successful downstaging therapy: A report of two cases

BackgroundNonobvious early symptoms are a prominent characteristic of pancreatic cancer, resulting in only 20% of patients having resectable tumors at the time of diagnosis. The optimal management of unresectable advanced pancreatic cancer (UAPC) remains an open research question. In this study, the...

Full description

Bibliographic Details
Main Authors: Lin Shang, Peng Li, Jie Fan, Chunning Zhao, Xiangying Niu, Qitian Bian, Zhilin Yuan, Yanlong Kong, Tingshun Zhu, Bin Xu, Jianxin Dong, Hongjun Xiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
unresectable advanced pancreatic cancer
downstaging therapy
chemotherapy
immunotherapy
PD-1 antibody
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.946266/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.946266/full

Similar Items