Effects of SP600125 and hypothermic machine perfusion on livers donated after cardiac death in a pig allograft transplantation model
Abstract Background Hypothermic machine perfusion (HMP) improves the quality of donor livers for transplantation, both in animal models and in clinical practice. Treatment with SP600125, an inhibitor of c-Jun N-terminal kinase (JNK), can suppress the JNK signaling pathway to alleviate donor liver is...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2021-02-01
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| Series: | European Journal of Medical Research |
| Online Access: | https://doi.org/10.1186/s40001-020-00472-9 |