The <it>in vitro </it>effect of gefitinib ('Iressa') alone and in combination with cytotoxic chemotherapy on human solid tumours
<p>Abstract</p> <p>Background</p> <p>Activation of the epidermal growth factor receptor (EGFR) triggers downstream signaling pathways that regulate many cellular processes involved in tumour survival and growth. Gefitinib ('Iressa') is an orally active tyrosin...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2004-11-01
|
| Series: | BMC Cancer |
| Online Access: | http://www.biomedcentral.com/1471-2407/4/83 |