Cytokine-mediated crosstalk between cancer stem cells and their inflammatory niche from the colorectal precancerous adenoma stage to the cancerous stage: Mechanisms and clinical implications

Cytokine-mediated crosstalk between cancer stem cells and their inflammatory niche from the colorectal precancerous adenoma stage to the cancerous stage: Mechanisms and clinical implications

The majority of colorectal cancers (CRCs) are thought to arise from precancerous adenomas. Upon exposure to diverse microenvironmental factors, precancerous stem cells (pCSCs) undergo complex genetic/molecular changes and gradually progress to form cancer stem cells (CSCs). Accumulative evidence sug...

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Bibliographic Details
Main Authors: Guanglin Cui, Ziqi Wang, Hanzhe Liu, Zhigang Pang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
cytokine
colorectum
tumorigenesis
stem cell
cancer stem cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1057181/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1057181/full

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