NPM1 as a potential therapeutic target for atypical teratoid/rhabdoid tumors

NPM1 as a potential therapeutic target for atypical teratoid/rhabdoid tumors

Abstract Background Atypical teratoid/rhabdoid tumors (AT/RTs) are highly malignant brain tumors with inactivation of the SMARCB1 gene, which play a critical role in genomic transcriptional control. In this study, we analyzed the genomic and transcriptomic profiles of human AT/RTs to discover new dr...

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Bibliographic Details
Main Authors: Ji Hoon Phi, Choong-Hyun Sun, Se-Hoon Lee, Seungmook Lee, Inho Park, Seung Ah Choi, Sung-Hye Park, Ji Yeoun Lee, Kyu-Chang Wang, Seung-Ki Kim, Hongseok Yun, Chul-Kee Park
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Cancer
Subjects:
Atypical teratoid/rhabdoid tumor
NPM1
Nucleophosmin
Online Access:http://link.springer.com/article/10.1186/s12885-019-6044-z

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http://link.springer.com/article/10.1186/s12885-019-6044-z

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