Expression of acid cleavable Asp-Pro linked multimeric AFP peptide in E. coli

Expression of acid cleavable Asp-Pro linked multimeric AFP peptide in E. coli

Abstract Background Difficult to express peptides are usually produced by co-expression with fusion partners. In this case, a significant mass part of the recombinant product falls on the subsequently removed fusion partner. On the other hand, multimerization of peptides is known to improve its prot...

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Bibliographic Details
Main Authors: Murad Mollaev, Artur Zabolotskii, Neonila Gorokhovets, Elena Nikolskaya, Maria Sokol, Andrey Tsedilin, Mariia Mollaeva, Margarita Chirkina, Timofey Kuvaev, Anna Pshenichnikova, Nikita Yabbarov
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Journal of Genetic Engineering and Biotechnology
Subjects:
Multimer expression
Asp-Pro cleavage
Alpha-fetoprotein
Recombinant peptide
Online Access:https://doi.org/10.1186/s43141-021-00265-5

Internet

https://doi.org/10.1186/s43141-021-00265-5

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