Prevalence and spectrum of cancer predisposition germline mutations in young patients with the common late‐onset cancers

Prevalence and spectrum of cancer predisposition germline mutations in young patients with the common late‐onset cancers

Abstract Background Pathogenic germline variants (PGVs) can play a vital role in the oncogenesis process in carriers. Previous studies have recognized that PGVs contribute to early onset of tumorigenesis in certain cancer types, for example, colorectal cancer and breast cancer. However, the reported...

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Bibliographic Details
Main Authors: Shaoyu Hao, Ximeng Zhao, Yue Fan, Zhengchuang Liu, Xiang Zhang, Wei Li, Hongling Yuan, Jie Zhang, Yanxiang Zhang, Tonghui Ma, Houquan Tao
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Cancer Medicine
Subjects:
cancer
Chinese
early onset
germline variation
Online Access:https://doi.org/10.1002/cam4.6445

Internet

https://doi.org/10.1002/cam4.6445

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