GKT137831 and hydrogen peroxide increase the release of 6-nitrodopamine from the human umbilical artery, rat-isolated right atrium, and rat-isolated vas deferens

GKT137831 and hydrogen peroxide increase the release of 6-nitrodopamine from the human umbilical artery, rat-isolated right atrium, and rat-isolated vas deferens

Introduction: The human umbilical artery (HUA), rat-isolated right atrium, and rat-isolated vas deferens present a basal release of 6-nitrodopamine (6-ND). The basal release of 6-ND from these tissues was significantly decreased (but not abolished) when the tissues were pre-incubated with Nω-nitro-L...

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Bibliographic Details
Main Authors: José Britto-Júnior, Rafael Furlaneto, Antonio Tiago Lima, Mariana Gonçalves de Oliveira, Beatrice Severino, Francesco Frecentese, Ferdinando Fiorino, Giuseppe Caliendo, Marcelo Nicolás Muscará, Gilberto De Nucci
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Pharmacology
Subjects:
human umbilical vessels
nitric oxide
xanthine oxidase
dopamine
nitrocatecholamines
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1348876/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2024.1348876/full

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