Non-catalytic signaling by pseudokinase ILK for regulating cell adhesion
Pseudokinase ILK is essential for dynamic communication between focal adhesion complexes and F-actin filaments. Here, the authors show that ILK regulates such communication by complexing with PINCH and Parvin to trigger F-actin filament bundling through previously unrecognized actin binding motifs i...
| Huvudupphovsmän: | , , , , , , |
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| Materialtyp: | Artikel |
| Språk: | English |
| Publicerad: |
Nature Portfolio
2018-10-01
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| Serie: | Nature Communications |
| Länkar: | https://doi.org/10.1038/s41467-018-06906-7 |