Inflammation-Independent Antinociceptive Effects of DF2755A, a CXCR1/2 Selective Inhibitor: A New Potential Therapeutic Treatment for Peripheral Neuropathy Associated to Non-Ulcerative Interstitial Cystitis/Bladder Pain Syndrome

Inflammation-Independent Antinociceptive Effects of DF2755A, a CXCR1/2 Selective Inhibitor: A New Potential Therapeutic Treatment for Peripheral Neuropathy Associated to Non-Ulcerative Interstitial Cystitis/Bladder Pain Syndrome

Interstitial cystitis (IC)/bladder pain syndrome (BPS) is a chronic bladder disease of unknown etiology characterized by urinary frequency and episodic and chronic pain. Analgesic treatments for IC/BPS are limited, especially for patients with non-Hunner (non-ulcerative) type IC who usually have poo...

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Bibliographic Details
Main Authors: Laura Brandolini, Andrea Aramini, Gianluca Bianchini, Anna Ruocco, Riccardo Bertini, Rubina Novelli, Patrizia Angelico, Anna Elisa Valsecchi, Roberto Russo, Vanessa Castelli, Annamaria Cimini, Marcello Allegretti
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Pharmacology
Subjects:
CXCR1/R2 receptor inhibitor
DF2755A
interstitial cystitis (IC)/bladder pain syndrome (BPS)
peripheral neuropathic pain
cyclophosphamide
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.854238/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.854238/full

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