SEMA3C drives cancer growth by transactivating multiple receptor tyrosine kinases via Plexin B1

SEMA3C drives cancer growth by transactivating multiple receptor tyrosine kinases via Plexin B1

Abstract Growth factor receptor tyrosine kinase (RTK) pathway activation is a key mechanism for mediating cancer growth, survival, and treatment resistance. Cognate ligands play crucial roles in autocrine or paracrine stimulation of these RTK pathways. Here, we show SEMA3C drives activation of multi...

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Bibliographic Details
Main Authors: James W Peacock, Ario Takeuchi, Norihiro Hayashi, Liangliang Liu, Kevin J Tam, Nader Al Nakouzi, Nastaran Khazamipour, Tabitha Tombe, Takashi Dejima, Kevin CK Lee, Masaki Shiota, Daksh Thaper, Wilson CW Lee, Daniel HF Hui, Hidetoshi Kuruma, Larissa Ivanova, Parvin Yenki, Ivy ZF Jiao, Shahram Khosravi, Alice L‐F Mui, Ladan Fazli, Amina Zoubeidi, Mads Daugaard, Martin E Gleave, Christopher J Ong
Format: Article
Language:English
Published: Springer Nature 2018-02-01
Series:EMBO Molecular Medicine
Subjects:
Semaphorin 3C
Plexin B1
prostate cancer
receptor tyrosine kinase
apoptosis
Online Access:https://doi.org/10.15252/emmm.201707689

Internet

https://doi.org/10.15252/emmm.201707689

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