Efficacy of MUC1-targeted CAR-NK cells against human tongue squamous cell carcinoma

Efficacy of MUC1-targeted CAR-NK cells against human tongue squamous cell carcinoma

IntroductionThe clinical efficacy of CAR-NK cells against CD19-expressing blood cancers has been demonstrated, and they have shown potential for treating solid tumors as well. However, the efficacy of CAR-NK cells for treating human oral tongue squamous cell carcinoma (OTSCC) has not been examined....

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Bibliographic Details
Main Authors: Xiaolan Lin, Tian Guan, Yun Li, Yanchun Lin, Guowei Huang, Yan Lin, Pingnan Sun, Congzhu Li, Jiang Gu, Haoyu Zeng, Changchun Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
iPSC-derived MUC1-targeted CAR-NK cells
oral tongue squamous cell carcinoma
mucin 1
chimeric antigen receptor (CAR)
induced pluripotent stem (iPS) cell
NK cells therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1337557/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1337557/full

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