Tracking fibrosis in myeloproliferative neoplasms by CCR2 expression on CD34+ cells

Tracking fibrosis in myeloproliferative neoplasms by CCR2 expression on CD34+ cells

In myeloproliferative neoplasm (MPNs), bone marrow fibrosis - mainly driven by the neoplastic megakaryocytic clone - dictates a more severe disease stage with dismal prognosis and higher risk of leukemic evolution. Therefore, accurate patient allocation into different disease categories and timely i...

Full description

Bibliographic Details
Main Authors: Giulia Pozzi, Cecilia Carubbi, Giuliana Gobbi, Sara Tagliaferri, Prisco Mirandola, Marco Vitale, Elena Masselli
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
myeloproliferative neoplasms
myelofibrosis
flow cytometry
CCR2
biomarkers
bone marrow fibrosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.980379/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.980379/full

Similar Items