Synthesis of New Polyheterocyclic Pyrrolo[3,4-<i>b</i>]pyridin-5-ones via an Ugi-Zhu/Cascade/Click Strategy

Synthesis of New Polyheterocyclic Pyrrolo[3,4-<i>b</i>]pyridin-5-ones via an Ugi-Zhu/Cascade/Click Strategy

A diversity-oriented synthesis (DOS) of two new polyheterocyclic compounds was performed via an Ugi-Zhu/cascade (<i>N</i>-acylation/<i>aza</i> Diels-Alder cycloaddition/decarboxylation/dehydration)/click strategy, both step-by-step to optimize all involved experimental stages...

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Bibliographic Details
Main Authors: Roberto E. Blanco-Carapia, Enrique A. Aguilar-Rangel, Mónica A. Rincón-Guevara, Alejandro Islas-Jácome, Eduardo González-Zamora
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Molecules
Subjects:
multicomponent reactions (MCRs)
Ugi-Zhu reaction
click chemistry
polyheterocycles
pyrrolo[3,4-<i>b</i>]pyridin-5-ones
5-substituted-1<i>H</i>-tetrazoles
Online Access:https://www.mdpi.com/1420-3049/28/10/4087

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https://www.mdpi.com/1420-3049/28/10/4087

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