Pulmonary delivery of siRNA against acute lung injury/acute respiratory distress syndrome

Pulmonary delivery of siRNA against acute lung injury/acute respiratory distress syndrome

The use of small interfering RNAs (siRNAs) has been under investigation for the treatment of several unmet medical needs, including acute lung injury/acute respiratory distress syndrome (ALI/ARDS) wherein siRNA may be implemented to modify the expression of pro-inflammatory cytokines and chemokines...

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Bibliographic Details
Main Authors: Makhloufi Zoulikha, Qingqing Xiao, George Frimpong Boafo, Marwa A. Sallam, Zhongjian Chen, Wei He
Format: Article
Language:English
Published: Elsevier 2022-02-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Pulmonary administration
Drug delivery
Nanoparticles
siRNA
Cellular uptake
Endosomal escape
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383521002999

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http://www.sciencedirect.com/science/article/pii/S2211383521002999

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