Spatiotemporal patterns of early afterdepolarizations underlying abnormal T-wave morphologies in a tissue model of the Purkinje-ventricular system.

Sudden cardiac death (SCD) is a leading cause of death worldwide, and the majority of SCDs are caused by acute ventricular arrhythmias (VAs). Early afterdepolarizations (EADs) are an important trigger of VA under pathological conditions, e.g., inherited or acquired long QT syndrome (LQTS). However,...

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Bibliographic Details
Main Authors: Mengya Yuan, Heqiang Lian, Pan Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0280267