Neurons Are a Primary Driver of Inflammation via Release of HMGB1

Recent data show that activation of nociceptive (sensory) nerves turns on localized inflammation within the innervated area in a retrograde manner (antidromically), even in the absence of tissue injury or molecular markers of foreign invaders. This neuroinflammatory process is activated and sustaine...

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Bibliographic Details
Main Authors: Huan Yang, Ulf Andersson, Michael Brines
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/10/2791