Evidence of MHC class I and II influencing viral and helminth infection via the microbiome in a non-human primate.

Until recently, the study of major histocompability complex (MHC) mediated immunity has focused on the direct link between MHC diversity and susceptibility to parasite infection. However, MHC genes can also influence host health indirectly through the sculpting of the bacterial community that in tur...

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Bibliographic Details
Main Authors: B Karina Montero, Wasimuddin, Nina Schwensow, Mark A F Gillingham, Yedidya R Ratovonamana, S Jacques Rakotondranary, Victor Corman, Christian Drosten, Jörg U Ganzhorn, Simone Sommer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009675