EphB4 monomer inhibits chronic graft vasculopathy in an aortic transplant model

EphB4 monomer inhibits chronic graft vasculopathy in an aortic transplant model

T cells and macrophages play an important role in the formation of allograft vasculopathy, which is the predominant form of chronic rejection in cardiac transplants. Arteries express Ephrin-B2 as a marker of arterial identity, whereas circulating monocytes express the cognate receptor EphB4, which f...

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Bibliographic Details
Main Authors: John T. Langford, MD, Luis Gonzalez, PhD, Ryosuke Taniguchi, MD, PhD, Anand Brahmandam, MD, Weichang Zhang, MD, PhD, Alan Dardik, MD, PhD
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:JVS - Vascular Science
Subjects:
Ephrin-B2
Eph-B4
Allograft
Allograft vasculopathy
Neointimal hyperplasia
Online Access:http://www.sciencedirect.com/science/article/pii/S2666350323000135

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http://www.sciencedirect.com/science/article/pii/S2666350323000135

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