Tumor microenvironment deconvolution identifies cell-type-independent aberrant DNA methylation and gene expression in prostate cancer

Tumor microenvironment deconvolution identifies cell-type-independent aberrant DNA methylation and gene expression in prostate cancer

Abstract Background Among men, prostate cancer (PCa) is the second most common cancer and the second leading cause of cancer death. Etiologic factors associated with both prostate carcinogenesis and somatic alterations in tumors are incompletely understood. While genetic variants associated with PCa...

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Bibliographic Details
Main Authors: Samuel R. Reynolds, Ze Zhang, Lucas A. Salas, Brock C. Christensen
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Clinical Epigenetics
Subjects:
Prostate cancer
Tumor microenvironment
Deconvolution
Epigenome-wide association study
DNA methylation
Differential expression analysis
Online Access:https://doi.org/10.1186/s13148-023-01609-3

Internet

https://doi.org/10.1186/s13148-023-01609-3

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