Unusual clonal evolution involving 5q in a case of myelodysplastic syndrome with deletion 5q 31 treated with lenalidomide

Lenalidomide is a very active drug in myelodysplastic syndrome with del (5q). We report such a patient treated with this drug who developed unusual complex cytogenetic abnormalities, which were elucidated by multi-FISH and FISH analysis as jumping translocations involving the long arm of chromosome...

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Hlavní autoři: Virginie Eclache, Anna Da Rocha, Génevieve Le Roux, Pierre Fenaux
Médium: Článek
Jazyk:English
Vydáno: Ferrata Storti Foundation 2008-02-01
Edice:Haematologica
On-line přístup:https://haematologica.org/article/view/4761