Insight into the Anticancer Activity of Copper(II) 5-Methylenetrimethylammonium-Thiosemicarbazonates and Their Interaction with Organic Cation Transporters

Insight into the Anticancer Activity of Copper(II) 5-Methylenetrimethylammonium-Thiosemicarbazonates and Their Interaction with Organic Cation Transporters

A series of four water-soluble salicylaldehyde thiosemicarbazones with a positively charged trimethylammonium moiety ([H<sub>2</sub>L<sup>R</sup>]Cl, R = H, Me, Et, Ph) and four copper(II) complexes [Cu(HL<sup>R</sup>)Cl]Cl (<b>1</b>–<b>4</b&g...

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Bibliographic Details
Main Authors: Miljan N. M. Milunović, Oleg Palamarciuc, Angela Sirbu, Sergiu Shova, Dan Dumitrescu, Dana Dvoranová, Peter Rapta, Tatsiana V. Petrasheuskaya, Eva A. Enyedy, Gabriella Spengler, Marija Ilic, Harald H. Sitte, Gert Lubec, Vladimir B. Arion
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Biomolecules
Subjects:
thiosemicarbazones
copper(II) complexes
cytotoxicity
organic cation transporters (OCT1–3)
inhibitors
Online Access:https://www.mdpi.com/2218-273X/10/9/1213

Internet

https://www.mdpi.com/2218-273X/10/9/1213

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