Expression level and subcellular localization of heme oxygenase-1 modulates its cytoprotective properties in response to lung injury: a mouse model.

Premature infants exposed to hyperoxia suffer acute and long-term pulmonary consequences. Nevertheless, neonates survive hyperoxia better than adults. The factors contributing to neonatal hyperoxic tolerance are not fully elucidated. In contrast to adults, heme oxygenase (HO)-1, an endoplasmic retic...

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Bibliographic Details
Main Authors: Fumihiko Namba, Hayato Go, Jennifer A Murphy, Ping La, Guang Yang, Shaon Sengupta, Amal P Fernando, Mekdes Yohannes, Chhanda Biswas, Suzanne L Wehrli, Phyllis A Dennery
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090936&type=printable