Hydrogen Sulfide Attenuates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease by Inhibiting Apoptosis and Promoting Autophagy via Reactive Oxygen Species/Phosphatidylinositol 3-Kinase/AKT/Mammalian Target of Rapamycin Signaling Pathway

Hydrogen Sulfide Attenuates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease by Inhibiting Apoptosis and Promoting Autophagy via Reactive Oxygen Species/Phosphatidylinositol 3-Kinase/AKT/Mammalian Target of Rapamycin Signaling Pathway

Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease worldwide. Hydrogen sulfide (H2S) is involved in a wide range of physiological and pathological processes. Nevertheless, the mechanism of action of H2S in NAFLD development has not been fully clarified. Here, the reduced lev...

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Bibliographic Details
Main Authors: Dongdong Wu, Peiyu Zhong, Yizhen Wang, Qianqian Zhang, Jianmei Li, Zhengguo Liu, Ailing Ji, Yanzhang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Pharmacology
Subjects:
hydrogen sulfide
nonalcoholic fatty liver disease
apoptosis
autophagy
signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.585860/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.585860/full

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