Prolonged repolarization in the early phase of ischemia is associated with ventricular fibrillation development in a porcine model

Background: Repolarization prolongation can be the earliest electrophysiological change in ischemia, but its role in arrhythmogenesis is unclear. The aim of the present study was to evaluate the early ischemic action potential duration (APD) prolongation concerning its causes, expression in ECG and...

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Bibliographic Details
Main Authors: Olesya G. Bernikova, Alena S. Tsvetkova, Mikhail A. Gonotkov, Alexey O. Ovechkin, Marina M. Demidova, Jan E. Azarov, Pyotr G. Platonov
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1035032/full