Invasive Glioblastoma Cells Acquire Stemness and Increased Akt Activation

Glioblastoma multiforme (GBM) is the most frequent and most aggressive brain tumor in adults. The dismal prognosis is due to postsurgery recurrences arising from escaped invasive tumor cells. The signaling pathways activated in invasive cells are under investigation, and models are currently designe...

Полное описание

Библиографические подробности
Главные авторы: Jennifer R. Molina, Yuho Hayashi, Clifton Stephens, Maria-Magdalena Georgescu
Формат: Статья
Язык:English
Опубликовано: Elsevier 2010-06-01
Серии:Neoplasia: An International Journal for Oncology Research
Online-ссылка:http://www.sciencedirect.com/science/article/pii/S147655861080003X