Ultrastructure of noise-induced cochlear synaptopathy

Abstract Acoustic overexposure can eliminate synapses between inner hair cells (IHCs) and auditory nerve fibers (ANFs), even if hair-cell function recovers. This synaptopathy has been extensively studied by confocal microscopy, however, understanding the nature and sequence of damage requires ultras...

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Bibliographic Details
Main Authors: Daniel J. Moverman, Leslie D. Liberman, Stephan Kraemer, Gabriel Corfas, M. Charles Liberman
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-46859-6