Glioma angiogenesis is boosted by ELK3 activating the HIF-1 $$\alpha$$ α /VEGF-A signaling axis

Glioma angiogenesis is boosted by ELK3 activating the HIF-1 $$\alpha$$ α /VEGF-A signaling axis

Abstract Background Clinical studies have shown that first-line use of anti-angiogenetic therapy can prolong progression-free survival but little progress has been made in extending the overall survival of the patients. We explored the role of ELK3 in glioma angiogenesis to improve and design more e...

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Bibliographic Details
Main Authors: Mou Yueyang, Hu Yaqin, Xue Guolian, Zhao Wenjian, Jiao Yang, Li Chen, Cao Haiyan, Chao Min, Deng Jianping, Dai Penggao, Zhu Hongli, Wang Liang
Format: Article
Language:English
Published: BMC 2023-07-01
Series:BMC Cancer
Subjects:
Glioma
Angiogenesis
ELK3
VEGF-A
HIF-1 $$\alpha$$ α
Online Access:https://doi.org/10.1186/s12885-023-11069-w

Internet

https://doi.org/10.1186/s12885-023-11069-w

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