Associations between the <i>C3orf20</i> rs12496846 Polymorphism and Both Postoperative Analgesia after Orthognathic and Abdominal Surgeries and <i>C3orf20</i> Gene Expression in the Brain

Associations between the <i>C3orf20</i> rs12496846 Polymorphism and Both Postoperative Analgesia after Orthognathic and Abdominal Surgeries and <i>C3orf20</i> Gene Expression in the Brain

Considerable individual differences are widely observed in the sensitivity to opioid analgesics. We focused on rs12496846, rs698705, and rs10052295 single-nucleotide polymorphisms (SNPs) in the <i>C3orf20</i>, <i>SLC8A2</i>, and <i>CTNND2</i> gene regions that we...

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Main Authors: Daisuke Nishizawa, Makoto Nagashima, Shinya Kasai, Junko Hasegawa, Kyoko Nakayama, Yuko Ebata, Ken-ichi Fukuda, Tatsuya Ichinohe, Masakazu Hayashida, Kazutaka Ikeda
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Pharmaceutics
Subjects:
opioids
analgesics
single-nucleotide polymorphisms
orthognathic surgery
abdominal surgery
Online Access:https://www.mdpi.com/1999-4923/14/4/727

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https://www.mdpi.com/1999-4923/14/4/727

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