LncRNA CYP4A22-AS1 promotes the progression of lung adenocarcinoma through the miR-205-5p/EREG and miR-34c-5p/BCL-2 axes

Abstract Objectives Lung adenocarcinoma (LUAD) exhibits a higher fatality rate among all cancer types worldwide, yet the precise mechanisms underlying its initiation and progression remain unknown. Mounting evidence suggests that long non-coding RNAs (lncRNAs) exert significant regulatory roles in c...

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Main Authors: Liyao Dong, Lin Zhang, Xinyun Zhao, Hongling Zou, Sisi Lin, Xinping Zhu, Jili Cao, Chun Zhou, Zhihong Yu, Yongqiang Zhu, Kequn Chai, Mingqian Li, Qun Li
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Cancer Cell International
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Online Access:https://doi.org/10.1186/s12935-023-03036-z