Impact of Formalin- and Cryofixation on Raman Spectra of Human Tissues and Strategies for Tumor Bank Inclusion

Impact of Formalin- and Cryofixation on Raman Spectra of Human Tissues and Strategies for Tumor Bank Inclusion

Reliable training of Raman spectra-based tumor classifiers relies on a substantial sample pool. This study explores the impact of cryofixation (CF) and formalin fixation (FF) on Raman spectra using samples from surgery sites and a tumor bank. A robotic Raman spectrometer scans samples prior to the n...

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Bibliographic Details
Main Authors: Giulia Mirizzi, Finn Jelke, Michel Pilot, Karoline Klein, Gilbert Georg Klamminger, Jean-Jacques Gérardy, Marily Theodoropoulou, Laurent Mombaerts, Andreas Husch, Michel Mittelbronn, Frank Hertel, Felix Bruno Kleine Borgmann
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Molecules
Subjects:
Raman spectroscopy
machine learning
tumor bank
formalin fixation
cryopreservation
Online Access:https://www.mdpi.com/1420-3049/29/5/1167

Internet

https://www.mdpi.com/1420-3049/29/5/1167

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