B cell receptor repertoire analysis in primary Sjogren’s syndrome salivary glands identifies repertoire features associated with clinical activity

B cell receptor repertoire analysis in primary Sjogren’s syndrome salivary glands identifies repertoire features associated with clinical activity

Abstract Background Primary Sjogren’s syndrome (pSS) is a complex autoimmune disease featuring damage to salivary and lacrimal glands, with the possibility of manifestations across multiple organs. Antibody-producing B cells have long been appreciated to play a significant role in pSS pathogenesis,...

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Bibliographic Details
Main Authors: Ling Chang, Zihan Zheng, Yiwen Zhou, Kun Liu, Yinong Li, Bing Zhong, Zihua Zhao, Chengshun Chen, Can Qian, Qingshan Ni, Qinghua Zou, Yuzhang Wu, Jingyi Li, Liyun Zou
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Arthritis Research & Therapy
Subjects:
Sjogren syndrome
pSS
B cell
BCR
IgA2
Online Access:https://doi.org/10.1186/s13075-024-03283-z

Internet

https://doi.org/10.1186/s13075-024-03283-z

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