Preparation of Terbinafin-Encapsulated Solid Lipid Nanoparticles Containing Antifungal Carbopol<sup>®</sup> Hydrogel with Improved Efficacy: In Vitro, Ex Vivo and In Vivo Study

Preparation of Terbinafin-Encapsulated Solid Lipid Nanoparticles Containing Antifungal Carbopol<sup>®</sup> Hydrogel with Improved Efficacy: In Vitro, Ex Vivo and In Vivo Study

The present research was aimed to develop a terbinafin hydrochloride (TH)-encapsulated solid lipid nanoparticles (SLNs) hydrogel for improved antifungal efficacy. TH-loaded SLNs were obtained from glyceryl monostearate (lipid) and Pluronic<sup>®</sup> F68 (surfactant) employing high-pres...

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Bibliographic Details
Main Authors: Nilesh R. Rarokar, Sunil S. Menghani, Deweshri R. Kerzare, Pramod B. Khedekar, Ashish P. Bharne, Abdulhakeem S. Alamri, Walaa F. Alsanie, Majid Alhomrani, Nagaraja Sreeharsha, Syed Mohammed Basheeruddin Asdaq
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Pharmaceutics
Subjects:
solid lipid nanoparticles
hydrogel
antifungal
terbinafin
<i>Candida albicans</i>
Online Access:https://www.mdpi.com/1999-4923/14/7/1393

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https://www.mdpi.com/1999-4923/14/7/1393

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