4-Hydroxynonenal Contributes to Fibroblast Senescence in Skin Photoaging Evoked by UV-A Radiation

Solar ultraviolet A (UV-A) radiation promotes a huge variety of damages on connective tissues and dermal fibroblasts, including cellular senescence, a major contributor of skin photoaging. The mechanisms of skin photoaging evoked by UV-A partly involve the generation of reactive oxygen species and l...

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Bibliographic Details
Main Authors: Audrey Swiader, Caroline Camaré, Paul Guerby, Robert Salvayre, Anne Negre-Salvayre
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/10/3/365