Progressive Motor and Non-Motor Symptoms in <em>Park7</em> Knockout Zebrafish

Progressive Motor and Non-Motor Symptoms in <em>Park7</em> Knockout Zebrafish

DJ-1 is a redox sensitive protein with a wide range of functions related to oxidative stress protection. Mutations in the <i>park7</i> gene, which codes for DJ-1 are associated with early onset familial Parkinson’s disease and increased astrocytic DJ-1 levels are found in pathologic tiss...

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Bibliographic Details
Main Authors: Lakshmi Narasimha Murthy Chavali, Ingeborg Yddal, Ersilia Bifulco, Simen Mannsåker, Dagne Røise, Jack O. Law, Ann-Kristin Frøyset, Sushma N. Grellscheid, Kari E. Fladmark
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Park7</i>
DJ-1
zebrafish
Parkinson’s disease
behavior
NAD metabolism
Online Access:https://www.mdpi.com/1422-0067/24/7/6456

Internet

https://www.mdpi.com/1422-0067/24/7/6456

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