Altered tumor cell glycosylation promotes metastasis

Malignant transformation of cells is associated with aberrant glycosylation presented on the cell-surface. Commonly observed changes in glycan structures during malignancy encompasses aberrant expression and glycosylation of mucins; abnormal branching of N-glycans; and increased presence of sialic a...

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Bibliographic Details
Main Authors: Irina eHäuselmann, Lubor eBorsig
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00028/full